Is Anybody Being Prescribed Scopolamine For Depression (Page 5)

is anyone being prescribed scopolamine off-label for depression? the NIMH is doing clinical trials for same and apparently it works, however my p-doc won't prescribe it for me.

REPLY

REPORT

Why would anyone use scopolamine for depression? It's a very old drug that was used for many years during labor and delivery. Why? Because it's an amnesic drug that prevents the brain from recording memory so the mother's don't remember the pain. It caused women in labor to act so "wild" the use of scopolamine was discontinued and rightly so. I hope anyone looking to use this drug for depression will wait a very long time until a lot more research is done.

REPLY

Was this helpful? 1

I don't even know how to respond to your post... You have to be completely clueless about Big Pharma. There is NO MONEY in it for them, so why would they try to have these drugs approved. THE NIH NIIIIIIHHHHHHHH is running trials for these drugs because they work better than anything on the market. That's right with tax payer dollars, we are paying for these studies. Ketamine and Scope have better safety and efficacy profiles than many of the approved drugs, but we cannot have them because big pharma can't make a DIME off them. Next time do a little reading "DD" on what you post about. Nothing worse than someone who offers advice about something they are utterly clueless about. Save that BS for fox news. There are hundreds of herbel supplements that work better and are cheaper than approved drugs for many ailments... but no money for big money, so no trials. Clueless, uninformed people like yourself are the reason why things like bacterial resistance are such a problem. Read a little more before you offer any advice.

REPLY

Was this helpful? 0

david you are 100 percent correct... I have been using scopolamine made at a compound pharmacy for 7 years it is a miracle for me. Others should really do their research!

REPLY

Was this helpful? 1

Well, my skin is getting effed up from these patches. All leaving horrible welts that seem to be taking forever to fade. I am going to hold on to what I have left in case of emergency, but this isn't a workable solution. I don't know if I'm allergic to the scop or something else in the patch itself. I still have some scop tabs of 0.4mg left, but that didn't seem to make a difference in terms of mood and then added the constipation factor. I thought about sniffing a tab and see what happens, but considering my skin reaction, I think it my mess up my nose and I already have sinus/allergy problems. Plus I've never snorted a drug in my life and the idea is not appealing. If anyone can think of any other ways to take this drug safely, let me know. Very disappointing.

REPLY

Was this helpful? 0

Callie, can you get your doctor to consider prescribing the encapsulated form of scopolamine ordered from a compounding pharmacy?

Michael

REPLY

Was this helpful? 0

Hi Michael,
I'm sure she would, however, since she's just a GP, she didn't have any idea of the connection between scop and depression, and thus, she was just willing to try this for me. She wouldn't know what dosage to RX me. The other thing is, what if I am actually allergic to the scop? I have no way of knowing if it's the scop or some other substance in the patch like glue. If I am allergic to the scop, it probably isn't a good idea to try it in a different form. This is so frustrating because this was the first thing in a long time that lifted my mood.

REPLY

Was this helpful? 0

Hi Helen, I too have been having some success with scopolamine. I have been using the patch and have some questions about the pills if you would not mind. I've never used a compounding pharmacy before, is it much of a hassle or ex pence to do so? I am pretty sure that the patches help me but they cost me about 10 dollars each. I also wonder if they are giving me a high enough dose. The studies which have been published use an iv so it is a high dose over a short time. The patches I think give a lower dose over a much longer time. What size are you pills how much scopolamine do you take at a time? My doctor has been pretty willing to work with me on this and it would be great if we had more doseing options should I need them down the road. Thanks!

REPLY

Was this helpful? 0

Hi I have been taking it and now can no longer get the medication. I would appreciate more information about the compound pharmacy. I am also curious to know how much and how often everyone is taking it. It has been a life saver for me!!!

REPLY

Was this helpful? 0

Just an update. I've determined I'm not allergic to the scopolamine, just the ingredients in the patch. Most likely it is a chemical called polyisobutylene listed on the package. I Googled it plus rash and hit on a couple things about causing contact dermatitis. So, I've tried just letting the tablets dissolve under my tongue. I get no effect/relief that way like I did with the patch. So far I've tried 2 pills (Scopace) before bed. That would be a total of 0.8mg. I don't understand why that has NO effect when 1 patch delivers approximately 1mg over the course of 3 days (fyi - even though it contains 1.5mg, apparently only 1mg gets absorbed which I read). I am really puzzled and frustrated. Knowing I felt better with the patch is making feeling depressed even worse because I had relief.

REPLY

Was this helpful? 0

Hi Michael,
First, thanks for all your posts. I am sure it takes lots of time and your input has been invaluable.

I just spoke with Dr. S. Wow, how refreshing. She took as much time as I needed over the phone (am travelling to see her) and was so kind. Thank you for the referral. I thought folks might want to know that she is now booking out as far as the END of July!

REPLY

Was this helpful? 0

I'm posting again to please ask for anyone who is taking Scopolamine by pill/sublingual to please tell me the dosage and schedule that has helped you. I am desperate for relief and I've just lost a couple pets in the past month and am terribly sad. I'm so tempted to stick a patch on, but I'm allergic to that darn glue!!! I've now tried up to 4 tablets sublingual (that's a total of 1.6mg of scop) with no relief. I'm trying 5 right now to see if that helps. Please, nothing else has worked for me besides this patch. I need an equivalent dose...

REPLY

Was this helpful? 0

Thank you all for your input. I'm trying the Scop patch, started 36 hours ago. Some dry mouth, drowsiness, hot flashes --all past now. No noticeable relief from depression. I'm hoping for noticeable relief? I'll let you know how it goes after a few more days. Best of luck to all of you.

REPLY

Was this helpful? 0

This is a follow up to my post above. Six days of Scopolamine cause no improvement in depression. On the seventh day, yesterday, I doubled the dose - I have a body mass double that of many adults. Within eight hours I had experienced all the symptoms I mentioned on the 1.5mg dose, times two. This morning I looked in the mirror to find my pupils dilated, quite a bit of dizziness. The side effects seem to have resolved themselves, my pupils are no longer dilated. I am definitely not as depressed today as I was before I doubled the dose.

REPLY

Was this helpful? 0

I have been using nasal ketamine for two months. I have noticed some mild calming effects from it, but no real improvement in my depression. I know two other people who have had similar results.

Think twice before you spend a lot of money getting nasal ketamine.

REPLY

Was this helpful? 0

I have had success taking 0.8 mg of scopolamine hydrobromide (capsules made at a compounding pharmacy). I take 1 at bedtime 2 nights in a row and repeat that 5 and 10 days later for a total of 6 pills. Works for me and lasts 3-4 months but everybody reacts differently. Minimal side effects as its while im asleep, and mostly gone by morning. Should only do this under dr.s prescription and supervision as it has many interactions with other things, even over the counter and supplements...best of luck to you, hope u find relief.

REPLY

Was this helpful? 0

Are you male or female? What is your weight and age? Thank you.

REPLY

Was this helpful? 0

Thanks for replying wellagain. The pill form at that dose did nothing for me except cause constipation (swallowing, not letting dissolve under tongue). I did let 5 pills dissolve under my tongue before bed (total of 2.0mg) and my mood was better the next day but it didn't last real long

REPLY

Was this helpful? 0

Is there no one who makes the scop patch that doesn't have that particular chemical in it?? Another idea I had, and this is a little out there, is to take the patch (wear non-latex gloves) cut the "band-aid" adhesive off and use tegaderm over the scop instead. I don't think tegaderm has that chemical in it but u might want to double check. I know that sounds like a lot of work but, if it works then it's worth it. I'm a RN and we do weird stuff like that all the time...it's called "critical thinking" LOL.

REPLY

Was this helpful? 0

As far as I know, the scop patch is only made by Novartis. There is no visible way to remove the medicine from the adhesive. My only other idea was to crush a pill, mix with a little water into a paste and put under a band-aid. Would that absorb as well into the skin? I don't know. I've never had a skin allergy to regular bandages, etc, just these transdermal things.

REPLY

Was this helpful? 0

For those who can not use a patch or a pill there may be another option. I was looking at the websites of some compounding pharmacies and some said they can make up an ointment. It would be delivered trough the skin like the patch but not have the adhesive that some are allergic to. I have not tried this myself.

REPLY

Was this helpful? 0

I've been reading, and posting about Adderall, specifically Amphetamine Salts vs. Amphetamine IR. I think I need to ...

5 REPLIES

My ex is telling everyone at my work (Hannaford) that I'm prescribed suboxone. If they fire me for that how can I su...

9 REPLIES

I am being prescribed methadone for opiate addiction been of all other drugs for 4 years I'm in the process of tryin...

47 REPLIES

I used to get hydrocordone in white oval shaped pills. Now they come in peach color with a V on one side and 3605 on the...

2 REPLIES

I had back surgery a few months ago for two ruptured disc pushing on a nerve. Now I'm physically addicted to the opi...

6 REPLIES

## What is Cispin? ## Cispin is a common misspelling for the antidepressant called Zispin SolTab. Active Ingredient: Mir...

3 REPLIES

My Son went to the Dr. for anxiety and depression, pristiq created more problems for him, panic attacks, insomnia, loss ...

13 REPLIES

I'm getting terrified after reading some Chantix horror stories and people who report never being the same after tak...

1 REPLY

IS ABILIFY SAFE TO TAKE FOR DEPRESSION/ANXIETY IN A 15 YR. OLD GIRL MY 15 YR.OLD DAUGHTER WAS TAKING LEXAPRO 20MG ONCE D...

1 REPLY

My doctor just prescribed Navane for me, but I do not have Schizophrenia. I have major depression disorder. I am worried...

1 REPLY