Nuvigil Side Effects (Page 6)

I'm having severe side effects from nuvigil. Muscle and joint pain with numbness and tingling down my arms.

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Geeze Louise. I took my first 250mg Nuvigil tab today and everything started out great. 55yo 10 year cpap user. Later in the day I stared to get jittery, clinching my teeth and confused. Reminded me of my recreational drug days. Ha Ha I got so uptight luckily I had some Klonopin to ease me down. Tomorrow I am taking half the dose. I think my Dr. started me out at too large a dose. I understand everyone is reacts differently. Tomorrow hopefully I'll return from the 70's. I'll let you all know.

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I started on the 150 mg doseage and yes felt like I had tons of energy the first day, even took something to sleep that night. The next couple weeks were great, I could do my college evening class and din't fall asleep reading the chapter, but then it seemed like it didnt help anymore. doctor increased the dose to 250 mg that I take half in the morning and the other half at lunch. I have noticed tingling in the forehead area almost all the time now. Has anyone else had this side effect?

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I started Nuvigil Tuesday and was miserably wired. Wednesay I had naseau and found my thoughts jumping and confusing. Wednesay was wonderful and I decided this med. was working miracles in my life. On Friday I felt overwhelming fatigue an hour after taking it. The worst side effect is my eyes turn red, irritated, constantly burning. My Dr. started me on it due the the chronic fatiue I suffer from Autoimmune Hepatitis and Sjogren's Syndrome. Is there anything with less side effects?

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I started taking Nuvigil about a week ago for Narcolepsy. It has done wonders for me as far as keeping me awake during the day. I did experience some nausea at first and a mild headache. One day, I had tingling in my face, and today I have a lot of bloating. These are all side effects I can live with if it keeps me awake. Will keep taking it for now

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Joint pain so severe I can't lift or bend my arms without wanting to cry. Hit my shoulders and elbow joints. Can't take it. That's only at 50mg, and my MD wants me to increase to 100mg?????

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I have been taking 150mg Nuvigil daily since June 2011 for narcolepsy without cataplexy (although starting to wonder now if it's not adult ADD). At first, was AMAZING (albeit the nausea, gas, and bloating). Then started to feel like I didn't take anything at all. Now I crash (hard) almost exactly 12-13 hours after taking. I've had the most unbelievable joint pain in both shoulders (right is worse than left), back spasms, and stiff neck. I decided to Google search "Nuvigil joint pain" and look what I found! Ugh... does this mean my miracle stay awake drug needs to stopped? I've been on a diet of Advil twice daily for the past couple weeks because of the joint pain.

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Hi Angela,
I started taking the Nuvigil with my Adderall that was losing it's effectiveness. It's been three days and the pain has started. I am going to ask my doctor for Provigil. From what I have read, Provigil does not have the same side effects as Nuvigil. The drug company changed the Provigil ingredients slightly so that they could keep the patent and that may have been a bad thing for some people.

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What was your dosage. i was doing fine with 150mg Nuvigil and 3 mg of Lunestra. Was still getting tired and the Nuvigil was increased to 250mg---Big mistake--nausea and metal taste over bearing. it takes almost a week to calm down. went to 50mg of Nuvigil.

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I have not been on Nuvigil 150 mg. for about 3 months for Narcolepsy It's still working fine for me. I was sore for a while, but I started exercising which seems to help with the soreness. I have also changed what I eat and added more protein. Do not know if this has made a difference or not, but I do not have the nausea anymore.

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I've been on 150mg since June 2011. The pain didn't start until a few weeks ago and it's been pretty severe. I went to the sleep doc yesterday and he switched me to Provigil, twice daily (100 mg each). Unfortunately, the copay is now $75 per month! Nuvigil was only $20 with their discount card. I'm still debating on whether or not this would be a good investment.

I asked about getting on an ADD medication instead since it's been noted that people are often misdiagnosed. He strongly advised against me starting amphetamines because of their addictiveness. He would prefer to try Provigil first and see if it helps.

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Hi Mark,
I was on 50mg. of Provigil. I am a fairly small person and I am very sensitive to medicine. It doesn't take much for me.

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Hi Angela,
I thought Provigil would be less expensive since it is older than Nuvigil. I have a prescription for Provigil sitting at the pharmacy.

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I was thinking the same thing! Even my doc said "it's almost generic now, so should be no problem!" Well, it's a BIG problem! Now I'm faced w/the decision of sticking w/my $20 Nu that causes ADD & severe joint pain, or sucking it up and spending an add'l $55/month and hope it doesn't do the same thing!

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I started taking Nuvigil several months ago as amphetamine replacement. I found that, while it does keep me awake with less of the mania symptoms, there have been some strange side effects. At first extreme muscle soreness, which subsided. Then I was feeling very disoriented and strange for awhile, which subsided. Then I felt like my arms would go so weak at time I could not lift a coffee mug with one hand. That also subsided. I was still sleepy so my dosage was increased from 150 to 250. I find one 250 gets me all the way through morning, afternoon and evening - vs taking two smaller doses in a day which caused me to stay up very late. For awhile I had no side effects. The past two weeks or so I've experienced something strange: when something or someone startles me I have an all-body tingling sensation which is like a million needles pricking for a moment. It's pretty intense. Also I've become much more aware of people getting in my personal space, especially standing behind me.

All of this being said, I still value the positive effects enough to keep taking Nuvigil. It's helped me keep my job and be more focused on tasks at hand. I don't think I'm ADD because I always did very well academically, but I could be wrong ...

Regardless, I'm interested in learning from anyone who has encountered these side effects and/or discovered an alternative method, etc.

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he's probably right. Those amphetamines are very brutal on the mind and body. I've been through every one of them. awful! :(

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ok,so I'm not the only one going crazy with the joint pain. Severe...hit my shoulders and elbows to the point I couldn't lift anything up that pulled on my arms. Had a full blood work up....seems my vitamin D level dropped some since starting nuvigil. Never had that happen before. Doc says that caused the joint pain???? sooo confused.

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omg, I just went through this! Wasn't sure if it was Nuvigil or not...but it is the only explanation. Had full blood workup...neg of course....except vitamin d level dropped some (never happened before). I couldn't lift OR bend my arms...I couldn't even tolerate them touching the bed while lying down trying to sleep. I was about in tears and I have a pretty high tolerance for pain. :( New it was a bad idea. I developed permanent fibromyalgia while begininning on provigil years back when I was first diagnosed....and docs couldn't figure it out then even though I insisted it had to be the drug, because they kept on insisting to increase it and the more they did the worse I got.l...to the point I couldn't even walk. It was awful!

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omg, please stop it. I developed permanent painful fibromyalgia that began with provigil treatment and worsened with dose increased. Docs just wouldn't listen. I'm stuck with it, and doc insists on trying me on nuvigil starting low at 50mg then increase to 100. Result? sever joint pain in arms/elbows and shoulders, pain shooting down my legs...horrible! I'm done!!!

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I should have mentioned this is well. When I developed fibromyalgia with provigil treatment, I also developed RLS and Cataplexy all at the same time. Sounds like you may be having some early signs of cataplexy. My cataplexy remained undiagnosed for the next several years and became severe. You know why docs didn't diagnose it? They U kept asking me if i fell down following any strong emotion. I never fell because I was never standing up!!!! I could hardly walk (mostly from the muscle/joint pain/stiffness)! Docs kept doubting what I was saying regarding the pain as my many many tests all kept coming back negative. All my cataplexy episodes happened while sitting.
When the fibromyalgia, rls, and cataplexy were finally diagnosed and treated, things began to turn back around completely. Anyhow, Watch out for that tingling and muscle weakness. They were my warning signs of an impending cataplexy episode, lol. ( Xyrem has removed the cataplexy completely, thank God!)

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Well, I went to pick up my prescription for Provigil. Insurance didn't cover b/c doc did not call insurance company first. $154.00. I left it at the pharmacy.

I'm still on the Adderall XR, have not and don't want to increase. Some days I pass out in the afternoon, some days I make it through okay. This inconsistency makes it difficult to work. Using the Nuvigil (with the Adderall) caused the usual muscle pain. It was too much and I have a high tolerance for pain since I have Fibromyalgia and live with pain every waking moment. Provigil may not be the answer either. Waiting for research to provide hypocretin replacement.

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