My doctor gave me prestiq about 6 weeks ago, because we were having no luck controlling my hotflases with hormones. I had a complete hysterectomy @ 37 a year ago and the flashes were a nightmare! This medicine almost COMPLETELY stopped the hotflashes and helped with the mood swings! I was amazed that an antidepressent was the answer! FYI, I also sleep better and have been diagnosed with figromyalgia, which the symptoms are a little more tolerable.