increase in pain-added 50mg pain patch. I'm trying to keep oxycodone (10mg) at a minimum (2/5hr). Been using off & on for years (not every day, but now have to) Ihave trouble with my ears-called pharmicist and asked if this could be a side effect and he said yes and it is permanent damage. Is this fact? What should I do next? I had a toxic reaction to a medication that I had taken for years (daily). It was a low dose but I now know when you get older you have to be careful and not take asstrong a dose. I ended up 3 wks inhospital early this year and now I'm scared. I'm doing more research, but it is hard to find complete info you need to feel safe. I live in hawaii and the medical world here leaves a lot to be desired.