Rabeprazole is usually given for 4 to 8 weeks, unless directed by your doctor. Normally you take this medicine with a full glass (8 ounces) of water, with or without food. For more specific directions I would ask your M.D. that prescribed it to you.
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I believe it doesn't matter when you take it, as long as you follow the instructions. If you feel concerned I would go to your nearest pharmacist and ask he/she more specific instructions.
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