Miles Says:
Has any one else experienced this? I had to start using the Mylan version of Remeron / Mirtazapine and I now get sever leg cramps, headaches and the return of my depression. Its as though it has NO active ingredient in it. The name brand Remeron puts me to sleep about 15 min after taking it, but the Mylan generic for of Remeron/Mirtazapine does not. I stay awake for hours. I can not afford the name brand remeron at $187.00 a month but I am to afraid if I try to use the Mylan version again the worse will happen. I am kind of between a rock and a hard place over this. But I have switched back and fourth enough times now that I know the Mylan version does not work. I get this from Walgreens in IL and I am looking for similar problems. Walgreens tell me they will not carry another generic brand. They say Mylan is a trusted company in the generic medication business???
Mylan is a large and well known generic manufacturer - but what you're reporting is quite common as far as generic medications differing from their counterparts. Even generics with the same active ingredients coming from different manufacturers can react differently between individuals, and this is because the inactive ingredients and manufacturing process can actually differ. You might want to look around and see if you can obtain Mirtazapine from one of the other large generic manufacturers.
To name a few: Teva, Watson, EON Labs (now Sandoz), Roxane ... and there are more manufacturers of this medication than what I have just listed.
It's a pain that Walgreens only carries this particular brand. Check with other places to see who they carry it from.
To Amateur Neuropsych - Do you remember the manufacturer of the generic which you had that worked as well as the name brand?