Carol Leatherman Says:
I have been taking a new generic Macrobid for about nine weeks, It is my only medication change. Nine weeks ago I stated having heart palpations, sometimes prolonged and disturbing. The new capsules are black and cream, not the old bright yellow and black. Printed on the capsule is a large, italicized E and the numbers 122. Has anyone experienced palpations with this drug?
I was prescribed generic Macrobid the other day for a UTI, and I am experiencing side effects such as nausea, diarrhea and agitation, which never happened to me on the brand name Macrobid. I am calling my doctor about this today. I read that generic meds. can be 20% different in bioavailability. They are not the same as the brand name drug. I will stop this med. and never take it again. I would rather have the UTI.
3
Verwon Says:
[Moderator]
Saturday, 2/23/2008 11:41:33 AM
No, the difference is not in the Bioavailability, the 20% difference is allowed flat-out in the active ingredient!!!! In addition they do only have to be bioequivelent so they substance may be completely different from what you were previously taking. They only have to show that it works the same in the body as the name brand did, it does NOT have to be identical to the name brand.
So you may be getting an entirely different substance that your body is not used to or you may be getting more or less of a dose than you were previously taking.
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