http://www.prescriptiondrug-info.com/threads/HYDROCHLOROTHIAZIDE-D65142_s2.htm Recent Posts About HYDROCHLOROTHIAZIDE at The People's Medicine Community. if you do not take this medication for 3-5days can it cause water retention right away? en-us Copyright 2009 Prescription Drug Info All Rights Reserved. 11/21/2009 5:22:59 PM 20 http://www.PrescriptionDrug-Info.com/threads/HYDROCHLOROTHIAZIDE-D65142_s2.htm#161901 I am on Hydrochlorot for high blood pressure and if I go even one day without taking my pill I get swelling in the legs, it almost feels like something is sitting on my chest and I am very tired. Do not go a day without taking it. This is very dangerous and can cause problems if not taken every day! Tue, 21 Oct 2008 06:51:50 -0800 http://www.PrescriptionDrug-Info.com/threads/HYDROCHLOROTHIAZIDE-D65142_s2.htm#144397 Yes,I agree,especially during the warmer days. Also I noticed that after when I don't take it and I have a day where I sat for a while that my socks along my calf leave a mark. Has anyone else experienced this same problem? BUT I found a solution. My Dr prescribed a NON medicated fix which is comforatble. I wear medical legwear during the day even when I am sitting,ie..at my desk's pc working or standing at the sink doing dishes. Please let me know what anyone else found. Tue, 25 Apr 2006 23:47:34 -0800