Palifermin

Palifermin Article Summary

Palifermin (kepivance, Amgen) Is A Human Recombinant Keratinocyte Growth Factor (kgf) Produced In Escherichia Coli. When Patients With Blood Cancers Undergo High Dose Chemotherapy And Radiation To Undergo Bone Marrow Transplant, They Usually Get Severe Oral Mucositis. Palifermin Binds To Epithelial Cell-surface Receptors And Stimulates Epithelial Cell Proliferation, Differentiation, And Upregulation Of Cytoprotective Mechanisms. It Reduces The Incidence And Duration Of Severe Oral Mucitis By Pro ...

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Injection 6.25mg, 60mcg/kg/day

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Kepivance Palifermin

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Drugs/Palifermin.asp Last Updated June 27 2005

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