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Prednisone

First Approved by the FDA: January 17, 1972
Pharmaceutical Company: WATSON LABS






Prednisone Article Summary

Prednisone Is A Synthetic Corticosteroid Drug That Is Particularly Effective As An Immunosuppressant, And Affects Virtually All Of The Immune System. It Is Used To Treat Certain Inflammatory Diseases And (at Higher Doses) Cancers, But Has Significant Adverse Effects. It Is Usually Taken Orally But Can Be Delivered By Intramuscular Injection Or Intravenous Injection. It Has A Mainly Glucocorticoid Effect. Prednisone Is A Prodrug That Is Converted By The Liver Into Prednisolone, Which Is The Activ ...

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This article is from Wikipedia. All text is available under the terms of the GFDL
(GNU Free Documentation License) | http://en.wikipedia.org/wiki/Prednisone



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Prednisone
My husband died in our living room and I called 911. He was revived after they broke 3 ribs and had a major surgery and was hospitalized for weeks. When I panic I get short of breath. After Bill (husband) was taken to the hospital I had a panic attack and couldn't breathe. I called 911 and ended up in the hospital myself. At no time did anyone ask me about my history, what happened or anything. They just began giving me Prednisone. I had no idea what it was and took it. The take-down dose when I left the hospital was 20 mgms. three times a day for a certain period, then 10 mgms for another period and now I am down to 5 mgms per day and have been taking it for over a year. The hospital refuses to tell me what the dosage was when I was hospitalized but because of the 60 mgm daily take-down dose I know it must have been a great deal. All my life I have had shortness of breath when I panic but no one ever asked me. No history of any kind was ever taken...I was just given the Prednisone. On top of that, when I was released from the hospital the doctor who had been treating me refused to see me any longer and told me to find another doctor. At that point in time I did not realize the damage that had been done and I wrote him a letter telling him I did not blame him. In retrospect, I now realize that he knew he had overdosed me with Prednisone and he was afraid to do anything else so he simply refused to see me any longer. I can only imagine that the hospital dosage must have been huge and by the time I had reduced the dosage to 5 mgms daily the damage was done. A side effect of this medication is that I have lost my short term memory. The loss was immediate after taking the medication. I have to write everything down and post notes near wherever I happen to be working or sitting so that I don't forget to do anything, i.e., put the bread in to bake when it is raised enough. I have always been a very smart and alert person and I am now a woman who can no longer remember anything for more than a minute or two...and then the memory is gone. There are those who think this was caused by my age (I was 73 then) but I can assure you I was not then, and am not now, the least bit senile. This medication caused an almost overnight loss of short term memory to the point where it frightens me. I will be 75 in August and no longer drive simply because I think that old people cause accidents because their driving skills deteriorate with age. In addition to this, I now have a problem with my hands shaking. Most of the time the shaking is so bad I cannot write. My penmanship is a disaster. I have been given a tranquilizer for the shaking and it works to a point but I can no longer do many of the things I was able to do prior to the administration of the Prednisone. I do not look upon these problems as being those of aging because the onset was too sudden...and it immediately followed the high dosage of the Prednisone I was given in the hospital. To be perfectly truthful, whatever the dosage was when I was hospitalized, it enabled me to walk around, breath easily, and not tire. However, after a very short period of this feeling of wellbeing the other symptoms began to appear in rapid order. I have never been told what the dosage was while I was hospitalized and nothing appeared on the billing giving any indication. I would love to be able to take a subtitute for this drug but I am told there is not one. I do not like taking it but have found that I can no longer function without it. Changes in the weather have an effect on my breathing also. During the rainy season I have a much harder time than in the summer as long as the humidity is not too high. The more moisture there is in the air, the harder it is for me to breathe. I have been told that now that I am taking this medication I cannot stop and must continue with it as long as I live. I have to take vitamins to decrease the osteoporosis which I now have getting worse. Worst of all, I think, is that this medication causes depression and I find I have to fight that constantly. Surely there must be something I could take that would not destroy my life as Prednisone has done.
Thursday, 1/28/2010 7:47:34 PM  2 Replies RSS Feed for these replies
Body Aches
Does anyone know how long it take for this to get out of your body so that it doesn't hurt andymore. I don't like it.
Sunday, 1/10/2010 6:53:20 PM  1 Reply RSS Feed for these replies
Effects Of Prednisone.(prednisolone)
Im an 18 year old Male, supposed to be a fun time being 18 and all….but boy has prednisolone stuffed up my last year or so. Maybe i just react worse to this drug than some people, but the way its hit me has to be lived to be believed. The irritable uncomfortable feeling (even when your trying to relax on the couch), the anger and mood swings that are constant, the weight gain and wanting to eat all the time, the insomnia which makes you feel even worse for lack of sleep, the gigantic swelling in the face to make a once normal face a horror show, the fever which is so often there, the acne all over my body, the lack of confidence I now have, the depressing way you now interact with the ones you love, and one of the worst things to go through, the looking back and remembering how good it felt to be normal, and not knowing if you will ever have that feeling again..hmm i think its fair to say anybody on this drug for a fair amount of time has been through hell.
Thursday, 1/7/2010 6:57:08 AM  Post a Reply
Why Use Prednisone Is It A Cure All??
My mom suffers from cirousus of the liver and has rec bleeding which passes from her stomach .She has auto immuine also. Last year she had 8 bld transfusions. But when her blood gets low they always try prednisone . She also is diabetic this makes her sugar sky high is there no other way to treat this issue????
Thursday, 12/31/2009 10:38:10 PM  1 Reply RSS Feed for these replies
Prednisone Withdrawal And/or Side Effects
I am interested in hearing about any bad experiences with the prednisone. My husband has been taking it for 1 year. He started on 50mg and has been trying to taper all year but in the past his disease has flared up as the dose got lower and so it was increased again. This time he has been luck and got down to 10mg and then began losing his mind. In the last couple of weeks he has had panic attacks, mood swings, brain fades (moments of complete blankness where he is unable to talk/move or anything, inability to speak, dis inhibited behaviour and peculiar behaviour where he will simply repeats words over and over. His specialist says that it's the prednisone withdrawal and this will all improve as he tapers (he is down to 5mg now). He can't work or socialise which is so sad for our whole family for this time of year. Just wondering if anyone has had any experiences like this or knows of them?
Monday, 12/21/2009 1:58:47 PM  1 Reply RSS Feed for these replies
Gout
Is Prednisone ok for Gout treatment
Friday, 10/2/2009 7:57:53 PM  1 Reply RSS Feed for these replies
What Time Should I Take My Medicine
what time should i take my medicine wen it says take 1 pill 3 times a day and i already took one pill at 4:30
Tuesday, 9/29/2009 1:38:54 PM  Post a Reply
Presidone
i take it for itching,i have a high count of red blood cells.
Monday, 8/31/2009 1:45:31 PM  1 Reply RSS Feed for these replies
Optic Nerve Inflamation
My doctor has prescribed prednisone 10mg 4 times a day I just started taking it a few days ago my optic nerve is inflammed causing my vision in my right eye to be blurred and foggy.i seen a nuero opthsmologist at university of michigan medical center and he dida ton of tests he knew what was wrong but could not find what was causing i guess what i want to know is has anyone had this condition and has prednisone worked?
Sunday, 8/16/2009 7:37:14 PM  Post a Reply
Predisone Causes Pain In Chest
I have had stinits placed in the arteries and when I take predisone it makes my chest hurt.
Tuesday, 7/28/2009 7:34:38 PM  Post a Reply

Possible Dosages for this and Related Drugs:

Note: May Include Dosages for Drugs similar to Prednisone

Solution   5mg/5ml,  5mg/ml
Tablet   10mg,  1mg,  2.5mg,  20mg,  25mg,  50mg,  5mg

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    Drugs/Prednisone.asp Last Updated January 28 2010


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