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Methotrexate

First Approved by the FDA: August 10, 1959
Pharmaceutical Company: MAYNE PHARMA USA






Methotrexate Article Summary

Methotrexate (rinn) (pronounced /mtrkset/), Abbreviated Mtx And Formerly Known As Amethopterin, Is An Antimetabolite And Antifolate Drug Used In Treatment Of Cancer And Autoimmune Diseases. It Acts By Inhibiting The Metabolism Of Folic Acid. Methotrexate Replaced The More Powerful And Toxic Antifolate Aminopterin, And The Two Should Not Be Confused With Each Other. contents 1 Mode Of Action 2 Uses 2.1 In Cancer Chemotherapy 2.2 Medical Termination Of Pregnancy 2.3 Other Uses 3 Pha ...

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This article is from Wikipedia. All text is available under the terms of the GFDL
(GNU Free Documentation License) | http://en.wikipedia.org/wiki/Methotrexate



Recent Methotrexate Forums  Start a New Discussion  View All  

Steroid?
Is methotrexate a steroid?
Monday, 11/3/2008 8:09:22 AM  4 Replies RSS Feed for these replies
Hair Loss
I am on methotrexate 2.5 7 tablets once a week. I would like to know if anybody losing the hair due to the medication.
Monday, 11/3/2008 7:58:17 AM  1 Reply RSS Feed for these replies
Methotrexate Reaction
When I take Methotrexate (7.5 mg.) for my RA treatment, I get these swollen areas in the tissue, on my lower leg and sometimes in my forearms that will turn bright red (like a sunburn). It really is painful and seems to feel better once it turns red. This will last up to 4 days. Anyone out there with a similar re-action?
Friday, 9/26/2008 10:00:53 PM  5 Replies RSS Feed for these replies
Patient
how long can this med keep your liver enames elevated?
Wednesday, 2/27/2008 7:35:43 PM  Post a Reply
Combined Methotextrate And Interferon Usage.
Hi all, I'm interested in your opinions on this. I have MS.I also have rather severe Psoriasis. PA got pretty damn awful tbh. So I've went for Metho usage and I have Inter. as I mentioned. Now the concern , at the time, was my immune system being lowered, could potentially cause me to have another episode(MS progression).:/ But as I've said the pain was awful.Enough for me to risk further disability. Does anyone have any thoughts as to wether I should be worried besides what I've mentioned?
Sunday, 3/4/2007 3:27:34 PM  1 Reply RSS Feed for these replies
Methotrexate & Coumadin
I have the beginning signs of Rheumatoid Arthritis and my doctor has prescribed Methotrexate. I have been on Coumadin for 13 yrs. and I am concerned about the interaction between Methotrexate and Coumadin. Would it be a potentially dangerous combination?
Sunday, 7/2/2006 8:24:28 AM  1 Reply RSS Feed for these replies
Can You Take Herbs
What if any herbal supplements can you take while on certain drugs?
Thursday, 1/19/2006 11:15:41 AM  Post a Reply
Use As A Tx For Auto Immune Dis. Hearing Loss
Suggested use by MD for last ditch try to stop hearing loss due to auto-immune disease. Has anyone used this for this tx? If so, what about results/sideffects
Saturday, 7/9/2005 11:15:24 AM  Post a Reply
Methotrexate
I need to know the wording on FDA's black box for a transcript I'm working on. The lawyer is not intelligible
Friday, 7/8/2005 11:49:19 AM  Post a Reply

Possible Dosages for this and Related Drugs:

Note: May Include Dosages for Drugs similar to Methotrexate

Injection   1000mg,  100mg/vial,  1g,  1gm/40ml (25 mg/ml),  1gm/40ml (25mg/ml),  1gm/vial,  2.5gm/100ml (25 mg/ml),  2.5gm/100ml (25mg/ml),  2.5mg/ml,  20mg,  20mg/2ml (10 mg/ml),  20mg/2ml (10mg/ml),  20mg/vial,  250mg/10ml (25mg/ml),  25mg/ml,  500mg/20ml (25 mg/ml),  500mg/20ml (25mg/ml),  50mg/2ml (25 mg/ml),  50mg/2ml (25mg/ml),  50mg/vial
Powder   100%
Tablet   10mg,  15mg,  2.5mg,  5mg,  7.5mg

Related Drug Page(s):

  • Methotrexate Preservative Free Methotrexate Sodium
  • Methotrexate Sodium Preservative Free Methotrexate Sodium
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  • Rheumatrex Methotrexate
  • Trexall Methotrexate


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    Drugs/Methotrexate.asp Last Updated November 3 2008


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