New Opana Is Out Now - March 15 (Page 2) (Top voted first)

I got my new Opana Prescription this week and it is the new formulation. The old ones were six sided and the new one is round.

The new formulation, that the FDA approved, is supposed to be the same quality as the old Opana we are used to. I hope so.

I am going to include the links to the articles that discuss this at the bottom, the latest article is directly from the makers of Opana and is from February.

The old stock of Opana is all supposed to be gone from the shelves by now and the pharmacists are all supposed to be using the new formulation.

Let us know here how you think the new stuff is working for you. Is it the same as the old stuff? IS there a coating on the new stuff that changes its effectiveness like the way the new formulation of Oxycontin did when it came out in 2010? Let us know.

Mine only started a few days ago so it is too early to say. It is the Opana long acting. They had to change it to stop people from crushing and abusing them.

Let us see if it works.

here are the article links;

This one is from Endo Pharmaceutical directly, the company that makes the drug;

Crush-Resistant Formulation of Opana ER® Approved by the FDA

Here is the second one ;

Endo Announces FDA Approval of a New Formulation of Opana® ER Designed To Be Crush-Resistant

Hope it helps everyone!

Peace, Keith

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i took roxycodone for 5 years they do take the edge off,but they changed me to opana 40,s with the jell.not only do I throw up every time but sometimes it come,s out whole in my stool,they really make me sick.tired of being a guinie pig.

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I started taking the new formula of Opana in July. Since then I have been having horrible upper abdominal pains, nausea and vomiting. I went to my family Doctor; he told me I was constipated; which I did not feel. My test results showed abnormally low Lipase and Bilirubin (Direct) levels. I did not connect the two problems until I read some of the posts on here about the horrible side effects others are having with the new formulation of this drug. I do have a brain tumor and Chronic Shingles of the nervous system. I thought it was possibly the shingles causing the problem; but now, I am not so sure it isn't the medication. I had a bad reaction to the generic Opana & ever since I started taking this medication I have had problems with an upset stomach. Since the release of the new version. I throw up at least one a day out of two, which makes the chronic pain so much worse. To deal with the pain and the nausea both is a lot to handle. SO the plastic in the new formula can actually build up in your intestines? I think I found my problem, now just getting my Doctor's to agree to switch the medication will take a miracle.

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Well were should I start ,I got into a bad reck in 06. An I'm all screwed up I got to have help get in dressed ,long story short ,I go to health first medical center .an I was get in opana 40 s .....them pills took my pain away all day ,and now the new ones ant worth s*** !!!!!!an the FDA F***ED UP EVERYTHING !!!! NOW IM MISSERIBLE an I half to live like this

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Also, to everyone who thinks that the adverse reactions are made by up by drug abusers are wrong. Your body responds to everything you put in it. The human digestive tract did not evolve to digest plastic. There are many reasons why a person could have a bad reaction to the new formulations. Many responsible patients are reporting new and adverse side effects. If you are going to make such outrageous claims, you should at least have some evidence instead of an ignorant opinion.

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If you are having problems with the new Opana ER, you should ask your doctor to write you a script for the generic Opana ER that is manufactured by Actavis. A lot of people are unaware that a generic version exists.

Also, Endo created the new abuse proof forms to help them maintain their patents. The Opana ER patent was going to expire in 2013 and Endo needed a way to sell Opana ER as a name brand or else lose lots of money. So, they reformulated Opana ER and received a new patent. Why do you think there are so many legal battles going on between Endo and generic medicine makers.

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I sent an email to Endo corporate, and actually got a response from them that I was the ONLY ONE that has complained about the new formulation.

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yes i got my new prescription yesterday, so far they are making me soo sick on my stomach that i don't think im going to be able to continue takin. The first one i took didn't stay down an hour. I dont know what they did to the med but gettn ready to change, n if im not the only one endo pharm is going to b loosing alot of money cause ppl can't take that "snot" concocsion!!!! Smart move on their part...NOT. now i gota go bk to pm dr tomorrow to get something else. they lost my money.

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Tell me are there problems with new Opana like the new OxyContin?

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Its NOT the Docs that are full of it, its the goverment and the pharmacys-people that were abusing the old opanas didnt know how strong they were and some starting OD'ing. Plus pharmacys were getting robbed for opanas. Here in Ohio anyway.FMGIM

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Roni-Sorry your getting so sick from the new opana meds. When you said, what a waste of money...your NOT kidding. I mean I have insurance BUT! If it dosent come in a generic form then I have to pay more, more co-pay and it's not cheap!. These pills in my state anyway, (Ohio) are between $600-$700 for 60 pills if you dont have insurance. I do agree, Endo will lose some business ($$) like oxycotin did. They need to understand that some of us just can't do those damn fillers!

Roni, hope you feel better and hope your PM gives you something to help your pain.

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DO NOT FILL YOUR OPANA SCRIPS ANYMORE THE NEW 1s DO NOT HELP PAIN AT ALL!!!!!!

ENDO AKA OPANA.... YOU HAVE JUST LOST MY $$$ I TAKE OPANA ER 20MG 2Xs/DAY & OPANA ER 40MG 3Xs/DAY & W/O INSURANCE IT COST ME 1280.00 & 480.00 JUST FOR THESE 2 SCRIPS. WITH THE NEW FORMULATION THEY DO NOT HELP MY PAIN @ ALL! I HAVE LUPUS & I AM IN CONSTANT PAIN EVERYDAY & IF ANYONE ELSE IS HAVING THE SAME TROUBLE AS I AM JUST GETTING SOME RELEIF ENDO WILL BE BANKRUPT WITHIN 3MOS BC IM NOT PAYING FOR OPANAS ANYMORE BC THEY DO NOT WORK ANYMORE.

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Just FYI that the new opana ers suck just like oxycontins. I was on oxycontin 60s until they changed the formula and it no longer worked. My dr had to change all his patients to opana which worked wonderful. Just got my new opanas four days ago and am experiencing withdrawals now. Cannot believe after Endo made all this money off of people who used to take oxycontins that they would be stupid enuf to change it also. Going to be getting on another med so I don't waste money on new opanas and hope Endo loses money for changing formula and leaving people screwed. Does anyone know how to get coating off? Even tried chewing and still in pain and feel awful.

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I had to go back to my Dr in tears today. I gave the new Opana's a 6 day try and it was awful.
He put me on Oxycontin and I have never taken it before, not a high dose.
The new medicine (oxycintin) says OP on one side, are these generic?? They were given to me from pharmacist in the original Oxycontin bottle, but why do they say "OP"?
Thanks for information, I am concerned about taking a medicine that has such a stigma attached.
The other alternative is a medicine called "MS contin"

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The new 10mg don't work like the old ones did. How many do u have to take for them to work?

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Hi, I experianced the same effect that you did on this new opana. Shaky, annoyed ect.. My husband said I was being "mean"? Say what? lol. I have so much pain I dont need anymore problems-I swear I don't. I think if I stay on this new opana I'll end up getting a divorce! Him divorcing me! That happens and I promise you this...I will SUE Endo for ruining my life! Because it's endo that changed this med because of drug abusers and Im having problems taking it-AND now mental issues..WTF?

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They r changing all of the opanas to new formula. Also went to get my opana 10 mg immediate release filled when I took in my 40 ers and couldn't get the 10s filled at all becuz they have been discontinued until may due to changing the formula. Also am getting nauseas from the 40s and filed a complaint with Endo. They r trying to say its the same blah blah bs as the old formula. Good luck everyone.

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I would ask for Fentnyal (spelling?) patches. Ask your pharmacy to order the Milan brand patches. IMO they work pretty good. Was on them then doc put me on OCs, then opana. But if the opana is making you sick, I would recommend the patches. Good Luck

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This month I received the new version of Opana ER. I've been taking 3 of the 40 mg ERs for years, and suddenly they were changed without any real warning. Opana ERs have been the best pain med I've ever been prescribed (and I've taken a wide variety of them). I understand that Endo wants to protect itself from class action suits by families of people who OD by shooting it up or chewing them or whatever, but they are also hurting those taking them as prescribed for legitimate pain management. Here's what I've noticed regarding the differences between the old and new versions...

The old ones usually took about 45 minutes to start working and another 30 minutes to reach full strength. It would stay at that level for about 6 hours and then would rapidly drop off in terms of pain relief. It would go from working at full-strength to having no effect in the span of 30 minutes (on average). I rarely experienced mental cloudiness, unusual fatigue, nausea, or anything else like that.

The new version takes longer to start working (about 85 minutes give or take, compared to the old version's 45 minutes), then maybe 30 more minutes to reach full-strength. The new version only gets to about half the level of pain relief at its full strength compared to the old version. The new ERs do tend to last a couple of hours longer and drop off much more gradually. However, this new version feels like it's tearing my stomach up. About two hours after taking one of the new ones, my stomach starts hurting pretty badly and continues for hours.

So in addition to taking longer to start working, they only seem to be half as effective while causing stomach pain. I'm going to try to see my doctor next week to see what alternatives are available, though there's not much I haven't already tried. Endo took a perfectly good medication and messed it up. It was the best pain med I've taken -- not necessarily the strongest, but strong AND without much in the way of side effects. So now I guess it's back to the drawing board.

--C

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Well, I have been dealing with chronic pain for many, many years. Not only back pain but also fibro and the worst, CRPS. I was on oxycontin when they switched formulations on that and that made me sick and it lost pain-relieving strength so my doc switched me to Opana. I was thrilled, it worked very well!

Then they went and did the same thing here. I had hopes it would be different. Different company, different process. I was hoping mainly I guess because I didn't, and still don't, know what I would or could switch to next for pain relief. But after the first week of the switch the problems started, like most of you have reported.

It started about a week out and it started with stomach issues; cramping and nausea. Then came some problems with dizziness. Then came the lessening of pain relief. Within two weeks of starting the new opana it was all like this. That was around the middle of March I guess.

I have ruled out all of my other meds, changes in my pain issues, weather, etc. It all points only to the opana re-formulation. I hope my Doc has some ideas on what to try next because there aren't many opiod agonists out there that work well.

Good luck everyone. Hope you find some relief.

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INmorePain,
First let me say how sorry I am as well to others here for your pain-I'm sorry your suffering.
Unreal yet another person effected by the new Opana! I have been TRYING to deal with the new change of opana myself. I just got my new script about a week an a half ago, the 30 ER's. I too have had the upset stomach, been shaky, jittery? My husband said I have been "sharp" with him? LOL what else is new. But just want to tell you, not sure if it's me but does seem like it's subsiding?(spelling?) I think if you give the new formula a chance it may help. I also agree that it does NOT seem to help with the pain? It does BUT it dosent!? Just seems like it's "cheaper" If I can say that? Version of opana? Good luck finding this s*** in GENERIC! No way! lol.
OH DUH! LOL. I WAS on fentyl patches at one time and think I may ask my PM doc for them again . I have to say, for me-the patches worked pretty good. Why was I taken off? Due to hot flashes-summer time, combanation I guess? Then he put me on the opana-it worked great! Until they f***ed with it! (excuss my french)
Anywho-really hope you the best.
Have a great Easter!!

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