Linzess Weight Gain (Top voted first)

Updated

I was just prescribed Linzess for my IBS. I am wondering if others on this medicine have experienced wieght gain?

102 Replies (6 Pages)

Page:1Next PageLast Page
Earliest Newest Votes
9

I have just started taking Linzess for my IBS and I've noticed that I have less appetite and am actually loosing weight. Am I just the exception or should I expect to see this change over time?

Was this helpful? 49
7

I took Linzess for about 3 weeks back in the fall. The first week, I had diarrhea almost daily, and I lost a couple of pounds. I thought I had found a miracle cure for my chronic constipation and bloating. The next week, I was still having regular soft bowel movements, but I starting feeling bloated again and noticed I was gaining weight. I thought it was just water weight, so I kept taking Linzess for another week until I was smart enough to Google Linzess and weight gain.

I gained 7 lbs. in just under 2 weeks. I'm only 5'2", so that is a significant weight gain for me. Fast forward to 7 months later, and I'm still struggling to lose those extra pounds even with intense daily exercise. It's the most difficult excess weight I've ever battled...even after gaining far too much weight with both of my pregnancies, I was able to work out daily and bounce back fairly quickly. I can not get rid of this stupid Linzess weight and it's very frustrating. I would rather deal with constipation than the extra pounds.

Was this helpful? 35
10

I have been taking Linzess for about a month, because I have severe IBS. I guess I am the opposite as well. My beginning weight started at 218 and as of August 18,2014 , I weight 210. I weigh in every Monday. For me it is a life changer and saver as well. I have changed my diet as well. Fruit smoothie in the morning, one good meal and a fruit smoothie in the evening. I also read it takes about 12hours for all food to metabolize in fat and proteins, maybe thats why I have lost so much weight. I take my Linzess at the end of the day before going to bed, allowing it to perform a detox. Thank you Linzess.

Was this helpful? 24
2

I've gained 4 pounds in 3 days since I started taking Linzess. I am on weight watchers so I count points so I know it is not my food intake. I don't usually fluctuate in pounds so I think it's the new meds. I am still taking Miralax but it doesn't seem like either are working. I look pregnant now. It may take 2 weeks for the meds to work. I may need a higher dose. I'll give it a more time.

Was this helpful? 24
4

I had the same weight gain on 145 mcg of Linzess, four or five pounds the first week. Am finding it very difficult to lose that weight. Many others have complained of sudden weight gain. I called the manufacturer and informed them of same. I've discussed this with my doctor but we can't figure it out.

Was this helpful? 20
3

I started on Linaclotide a couple of weeks back. It isn't working very well at all, and I am constantly hungry. Anyone else having this result?

Was this helpful? 18
8

I have been (was) on linzess for 6 mos but wasnt taking it regularly. I noticed weight fluctuations. I was consistant as of april 2014 and i stopped taking it as of July 2014. I gained 20lbs. I was going to the gym 3-4 times a week. I put myself on a vegetable and seafood diet. nothing but continued gain. My average size was a 6. the largest i own in a 10 but not even the 10 will fit.

Was this helpful? 15
15

you should try 290 mcg... it works!! Take in the morning with an emptry stomach and within half hour eat somthing, be ready to go to the bathroom :)
Try having enough time for the process, i have also try taking it in the afternoon when my stomach is bloaded and it works.
IBS is the worse, just watch the changes closely to see what works for you!

May the Lord give you healing! amen

Was this helpful? 11
45

Can you tell me how u lost the weight
I just started today, I don't understand how these people gain so much if it cleans everything out.
Please let me know your thoughts on it thank you

Was this helpful? 11
13

Make sure the dessicant is in there. Those tablets are very moisture sensitive. Even on the webpage it says Only take in factory packaging. Wal-Mart is dumping those in regular prescription bottles

Was this helpful? 9
16

I have lost 13 pounds since starting Linzess last year. While I am grateful that it has helped dramatically with the constipation, I have found that my entire life revolves around when I take this medication. I am never hungry. And when I do eat (even half a bagel or something small) I have half an hour before the "getting sick" begins, and that lasts for hours.

I am now 102 pounds, and though I have been trying to eat more to get to 110, nothing is working.

I am so glad that you posted. I take 145 2x a day. Most people say they gain weight on this drug but I am withering away over here.

Was this helpful? 10
18

I have gained 22 lbs since I started on Linzess. I have NEVER had a problem with my weight. Even after having my children I lost all of that weight and had a flat tummy. Now my stomach is incredibly bloated!!!! I am not taking the Linzess anymore as of today!!!!!

Was this helpful? 9
20

I also gained weight and stopped taking it after one month. I am athletic and never have a problem with my weight but 145 mg Linzess made my abdomen bloated and painful and stopped working after the first week. I have been off it for a week and the bloating and weight gain has not gone away.

Was this helpful? 7
27

So you gained 20 lbs in July after stopping Linzess or you gained the weight starting in April to July while on Linzess ?

Was this helpful? 8
11

i just started linvess after being constipated for 27 days, however, with no weight gain. since linvess, i am gaining about a pound every other day. i am shocked and disgusted. i will finish this vial of 30 caps since it cost $265.(doctor did not tell me in advance) but don't want to renew it. there are other cheaper ways to induce diarrhea just like linvess!

Was this helpful? 6
19

Thank you for reply... Finally positive weight loss hope... I am already suffering with all the negative symptoms everyone is describing about bloating, slight weight gain and bathroom problems with my current medications(especially Wellbutrin).
My left is awful but now w/ Linzess only has to get better.. I can only get smaller and hv no more bloat.. Life has to get better after Linzess!! Your post was positive hope for me.

Was this helpful? 6
53

I have been on Linzess for 3-4 years and have gained 35 pounds on it. I work out, eat a strict diet, and even have a trainer and a dietician. I have been to a weight loss center and have had every lab drawn that could possibly attribute to this. I thought it was due to the Linzess and called the company 2 years ago and reported it. They said they have NEVER had this happen. Well looking at all the posts, this is not true. I was always thin and lost weight easily. Weight gain is not in my genetics. I am stopping the medication. I want to know or hear from those that have stopped it and would like to see if they lost weight after stopping Linzess and how long it took to lose the weight if so. TIA.

Was this helpful? 4
57

New medication out called Trulance. Appears to lack the side effect of weight gain.

Was this helpful? 4
6

Do you mean is it dangerous because it is beyond the expiration date? I doubt it. If you mean is it dangerous to use in general, no. From my experience, it is safe.

Was this helpful? 5
41

THANK YOU for this! I recently felt like I gained weight, which is weird for me because I work out for 90 minutes EVERY DAY and eat the cleanest diet ever. I haven't changed anything diet wise and couldn't figure out what the deal was... But now, just NOW it clicked... Perhaps LINZESS is causing the issue... And low and behold I see everyone saying that it does! Well... I am definitely NOT going to take it anymore. I am going to be GI DOC to tell him the issue... And we shall see. I swear this is a NEVER ENDING battle! :( Plus, Linzess is NOT cheap for me, so why would I spend so much $$$$$ to gain weight? Um. NO.

Was this helpful? 3
Page:1Next PageLast Page

More Discussions:

Linzess / Weight Gain and Other Meds Questions

I take thyroid meds and Migraine Meds....How do I ensure that the Linzess isn't "getting rid of" these meds ...

5 REPLIES
Linzess and weight gain

Type 1 diabetic, hypothyroidism, high blood pressure, allergies, glaucoma and constipation. What else? Taking Linzess. D...

1 REPLY
linzess causes weight gain

I am the same. I have lost 85 lbs over the last 1 year. I have gastroparesis. After 120 days on linzess I am up 15 lbs. ...

9 REPLIES
linzess weight loss

how long does it take to work ## Hello, Oscar! How are you? Linzess is not actually intended to be used for weight loss,...

9 REPLIES
linzess prescribed to help with weight loss

Hi! My Dr. Gave me linzess to help with weight loss. HOWEVER, I am reading all the posts about horrible weight gain, I a...

26 REPLIES
Linzess or other Drugs blocking weight loss

I eat very clean, rarely at restaurants. I have been on Linzess (Lazy bowels) for years, been on synthroid (subclinical ...

2 REPLIES
why would linzess cause weight loss

I have been on linzess for 2 months. I have lost 8 pounds (last time I checked). I'm a heavy female. Suffered with c...

2 REPLIES
Gain weight with thyroid medication

I have been on 50 mcg of levothyroxine for 5 months and I have gained 15 pounds. My doctor tells me that it should be th...

68 REPLIES
Gain Weight medicine

hi I am 31 years old with skinny body.my weight is just 34kg.I looks like athopian child whose arms and body is lean.I w...

2 REPLIES
Gain Weight Capsule

Ruchi here.i want to put put on weight currently my weight is only 43 kg. and want to put on up to 50 kg so help me is p...

1 REPLY